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Why are outcomes so important?

Why are "outcomes" so important?

Outcomes are important because if each different research study measures a different outcome, we are not able to compare the results or findings from each study.

  • For instance, imagine two studies looking at treatment of depression in teenagers:

    • In Study A, the researchers measure the amount of school missed and decide that if a teenager attended more school, their depression is improving or getting better.

    • But in Study B, the researchers measure the amount of energy teenagers have and decide that if a teenager had more energy, their depression is improving or getting better.

    • When the two studies are finished, we can’t compare or combine the results because they have used different outcomes.

 

  • When studies have different outcomes, it makes it difficult to compare treatments and decide if one treatment is better than another.
     

The IN-ROADS Initiative will give researchers a list of outcomes that can be a part of all studies on adolescent depression.

Two clincians with 6 different outcomes (3 on each side), which do not match each other (symbolized by not equal to sign)

Here is a short video if you’d like to learn more about why patients and caregivers should be involved in core outcome set development.

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ABOUT US

IN-ROADS aims to establish a core outcome set (COS) for use in adolescent major depressive disorder (MDD) clinical trials assessing any treatment intervention. Development of an adolescent MDD COS for use in future clinical trials will improve outcome selection and measurement thereby ensuring comparability between trials and fostering meaningful comparisons of trials and meta-analyses. The COS will be developed based on the input of patients, caregivers, clinicians, researchers, policy makers, and key international stakeholders.

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Last Updated: April 2022 by the IN-ROADS Initiative Team.

Please note: Some content photography on this website are stock images and models used are for illustrative purposes.

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